Meryl Streep, who holds the record for the most Academy Award nominations of any actor, is making some changes to her real estate portfolio.

On Thursday, she put her Manhattan penthouse on the market for $24.6 million.

The four-bedroom spread on the far west side of Tribeca, next to the Hudson River, has been home to Ms. Streep, 69, and her husband, sculptor Don Gummer, 71, since 2006, when they paid $10.13 million for the apartment.  

They used their go-to LLC for the purchase—which they’ve used in the past for transactions in Manhattan’s Greenwich Village and California—according to property records that also showed Mr. Gummer’s name.

The almost-4,000-square-foot condominium is surrounded on three sides with a terrace and has floor-to-ceiling windows, direct elevator entry, a skylit entrance gallery and Brazilian walnut plank floors.

“The public areas have been carefully designed to emphasize flexibility, and pocket doors easily create private intimate rooms, or luxurious and gracious entertaining spaces,” reads the listing with Douglas Elliman’s Jan Hashey and Steve Halprin.

The brokers declined to comment.

From Penta: LGBTQ Investors Need to Consider Longevity, Liquidity, and Legacy

In December, Ms. Streep spent $3.6 million on a midcentury modern residence in Pasadena, California. The house has three bedrooms, three bathrooms, high ceilings, walls of glass, and retains many original features and architectural details, including its windows, doors and terrazzo floors, the listing said.

Ms. Streep has been nominated for an Academy Award 21 times, starting in 1979, and has won three.

She most recently starred in “Mamma Mia! Here We Go Again” alongside Cher. A representative for the actress did not immediately respond to request for comment.

Curbed first reported the listing.